Tom has given you the solution for the Enterprise version.
If you have workgroups, though, I believe that enabling large file support (> 2GB) is not available. You also didn't say whether it's the data extents or bi extents where you are having this issue. In both cases, you just have to add extents to the db (data and/or bi) for the workgroups version.
I should note that if it's the bi extents exceeding 2GB (even with large file support enabled), you may want to look at your batch code import programs and look into finding why you might have extremely large transactions (e.g the entire import is one big transaction).